Andrei-Ștefan Lia



Timeline

Postdoctoral Researcher - Balmus Lab Romania, Transylvanian Institute of Neuroscience, Romania

Bioinformatics Engineer - QIAGEN, Romania

Research Associate - University of Fribourg, Switzerland

PhD - Biology, Glauser Lab, University of Fribourg, Switzerland

MPhil - Genetics, University of Manchester, UK

BSc – Genetics, University of Manchester, UK


Andrei-Ștefan Lia

Andrei started his research career in the wet-lab, with his undergraduate and Master’s research experience focusing on Chronobiology. During his Master’s, he has also taken an interest in Bioinformatics, mostly working with RNA-seq data. For his PhD, his research focus has transitioned towards Neuroscience, specifically working on thermal nociceptive adaptation/habituation in C. elegans, where he developed hardware and bioinformatic tools for high-throughput thermal and optogenetic stimulation of worm populations, behavioural recording and analysis. Next, he spent 2 years working as a bioinformatician for QIAGEN, developing a wide array of analysis pipelines for clinical and pharmaceutical customers.

In the Balmus Lab, Andrei is interested in bioinformatics processing and analyses of data generated from various CRISPR experiments (CRISPR screens, base editor screens, CRISPRa/i, scCRISPR-seq), RNA-seq, scRNA-seq, spatial transcriptomics, GSEA and multi-omics integration.


Selected publications

A system for the high-throughput analysis of acute thermal avoidance and adaptation in C. elegans. full text

Lia, A. S., & Glauser, D. A. (2020), Journal of Biological Methods, 7(1), e129

Specific Ion Channels Control Sensory Gain, Sensitivity, and Kinetics in a Tonic Thermonociceptor. full text

Saro, G., Lia, A. S., Thapliyal, S., Marques, F., Busch, K. E., & Glauser, D. A. (2020), Cell Reports, 30(2), 397-408.e4

Identification of avoidance genes through neural pathway-specific forward optogenetics. full text

Marques, F., Saro, G., Lia, A. S., Poole, R. J., Falquet, L., & Glauser, D. A. (2019), PLoS Genetics, 15(12), e1008509